PGT-A vs PGT-M Cost in Thailand: What to Expect

When planning IVF with genetic testing in Thailand, one of the first questions is often: How much does PGT-A cost compared to PGT-M? While both tests add to the overall IVF budget, they serve different purposes and involve different laboratory processes, which can affect pricing. This guide explains the cost components, what to expect in quotes, and how to compare packages effectively.

At a Glance: PGT-A vs PGT-M

• PGT-A screens embryos for chromosomal abnormalities (aneuploidy). It is often recommended for women over 35, those with recurrent miscarriage, or repeated implantation failure.
• PGT-M tests for a specific single-gene disorder (e.g., cystic fibrosis, thalassemia) that one or both parents carry. It requires a prior genetic workup to develop a custom test.
• Cost drivers: PGT-M typically involves more upfront work (probe development) and may be more expensive per embryo than PGT-A.
• Packages: Many Thai clinics offer packages that bundle IVF with PGT-A or PGT-M, but the exact inclusions vary.

Understanding the Cost Components

To compare costs fairly, break down the total into these parts:

• IVF cycle costs: Stimulation medications, egg retrieval, and embryo culture are usually separate from genetic testing.
• Genetic testing fees: This includes the biopsy of embryos (often on day 5 or 6) and the laboratory analysis.
• PGT-M development: For PGT-M, a preliminary test must be created for each family’s mutation. This may be a one-time fee or included in the per-embryo price.
• Consultation and genetic counseling: Some clinics include this; others charge separately.
• Shipping and handling: If embryos are biopsied in one lab and sent to another for analysis, there may be additional logistics fees.

How PGT-A and PGT-M Costs Differ

PGT-A is a more standardized test, as it looks for common chromosomal issues. PGT-M is highly personalized, requiring the lab to design a test around a specific genetic mutation. This customization often leads to higher initial costs. Additionally, PGT-M may require testing of family members (e.g., parents or an affected child) to establish the test’s accuracy, which can add to the expense.

Per-embryo costs for PGT-M may also be higher because the analysis is more complex. However, some clinics offer packages that include a certain number of embryos, which can help manage costs if you have many embryos to test.

What to Look for in a Price Quote

When you receive a quote from a Thai clinic, ask for a detailed breakdown. Here are key questions to ask:

• Does the quote include the IVF cycle, or is it only for genetic testing?
• Are medications included? If not, what is the estimated cost?
• Is the biopsy fee separate from the analysis fee?
• For PGT-M, is the probe development fee included? Is it a one-time cost or per cycle?
• How many embryos are covered in a package? What happens if you have more embryos than the package allows?
• Are there additional fees for freezing or storing embryos after testing?
• Does the price include genetic counseling before and after testing?

Comparing Packages: What to Watch For

Some clinics advertise a single price for “IVF with PGT,” but this may not include all necessary steps. For example, PGT-M may require a separate consultation with a geneticist, which could be an extra charge. Also, if you need to re-test embryos due to inconclusive results, there may be additional fees.

When comparing packages, consider the total number of embryos you expect to have. If you are likely to have many embryos, a package with unlimited testing might be more cost-effective than a per-embryo fee. Conversely, if you expect only a few embryos, a per-embryo price might be lower.

Questions to Ask Before Committing

Before you choose a clinic, schedule a consultation to discuss your specific situation. Prepare questions like:

• What is the total estimated cost for my treatment plan, including all medications and procedures?
• Are there any hidden fees I should be aware of?
• How many embryos do you recommend testing, and why?
• What is your policy on refunds if no embryos are suitable for transfer?
• Can you provide a written quote that itemizes all costs?

Next Steps for Budgeting

Once you have a clear idea of the costs, you can plan your budget. Consider these steps:

1. List all potential expenses, including travel, accommodation, and time off work.
2. Ask your clinic for a detailed quote and compare it with at least two other clinics.
3. Factor in the possibility of needing more than one IVF cycle.
4. Check if your insurance covers any part of the treatment (though most international patients pay out of pocket).
5. Explore financing options if needed, but be cautious about high-interest loans.

Remember, the cheapest option is not always the best. The quality of the laboratory and the experience of the genetic team are crucial for accurate results. Take your time to research and ask questions.

Frequently asked questions

Is PGT-M more expensive than PGT-A in Thailand?

Generally, yes. PGT-M requires a customized test for a specific genetic mutation, which involves additional development work and may cost more per embryo. However, the exact difference depends on the clinic and the number of embryos tested.

What is included in a PGT-A package in Thailand?

A PGT-A package typically includes the embryo biopsy and the genetic analysis. Some packages may also include the IVF cycle, but this varies. Always ask for a detailed breakdown of what is covered.

Are there additional costs for PGT-M beyond the per-embryo fee?

Yes, PGT-M often involves a one-time fee to develop the genetic test for your specific mutation. There may also be costs for genetic counseling or testing of family members. Confirm these with your clinic.

Can I get a refund if no embryos are suitable for transfer after PGT?

Refund policies vary by clinic. Some may offer partial refunds if no embryos pass testing, but this is not guaranteed. Ask about the clinic's policy before starting treatment.

Continue your research

• PGT-A testing cost guide
• IVF cost planning
• Patient resources

Medical information notice: This article is educational and does not replace individual assessment, diagnosis, genetic counselling or treatment advice from a licensed clinician. Provider services, availability, fees and policies should be verified directly before booking.