How to Get PGT-M Testing for a Known Genetic Disorder in Thailand

If you carry a known genetic disorder and are considering IVF in Thailand, preimplantation genetic testing for monogenic disorders (PGT-M) may be part of your journey. This guide explains the general pathway—from genetic counseling to embryo biopsy—so you know what to expect and what to confirm with your clinic.

At a Glance: Key Steps for PGT-M in Thailand

• Confirm your genetic diagnosis and obtain your genetic test report.
• Have a genetic counseling session to discuss inheritance and testing options.
• Choose an IVF clinic that offers PGT-M and coordinates with a genetic laboratory.
• Undergo IVF stimulation, egg retrieval, and fertilization.
• Embryos are biopsied and sent for PGT-M analysis.
• Discuss results with your doctor and decide on embryo transfer.

Understanding PGT-M

PGT-M is a technique used during IVF to test embryos for a specific genetic condition known to be present in one or both parents. It is not a general health screen; it targets a particular mutation or chromosomal arrangement. PGT-M is different from PGT-A (aneuploidy screening) and PGT-SR (structural rearrangements). Your doctor will recommend the appropriate test based on your situation.

Step 1: Confirm Your Genetic Diagnosis

Before you can pursue PGT-M, you need a confirmed genetic diagnosis. This typically involves a blood test or other genetic testing that identifies the specific mutation. If you have not had genetic testing, or if your results are outdated, your clinic may ask you to repeat testing. Bring all relevant medical records, including genetic test reports, to your initial consultation.

Step 2: Genetic Counseling

Genetic counseling is an essential part of the PGT-M process. A genetic counselor or a doctor with genetics expertise will explain the inheritance pattern, the risk of passing on the condition, and the limitations of PGT-M. They will also discuss alternative options, such as using donor gametes or prenatal testing. This session helps you make an informed decision.

Step 3: Choose an IVF Clinic and Laboratory

Not all IVF clinics in Thailand offer PGT-M directly. Some clinics work with external genetic laboratories. When choosing a clinic, ask about their experience with PGT-M, their success rates (though these are not guarantees), and how they coordinate with the lab. You may also want to ask about the laboratory’s accreditation and turnaround times.

Step 4: IVF Cycle and Embryo Biopsy

Once you are cleared for treatment, you will undergo an IVF cycle. This involves ovarian stimulation, egg retrieval, and fertilization with sperm (either from a partner or donor). On day 5 or 6 after fertilization, a few cells are removed from each embryo (biopsy) and sent for genetic analysis. The biopsy is performed by an embryologist, and the embryos are frozen while you wait for results.

Step 5: Receiving Results and Transfer

The genetic laboratory will analyze the biopsied cells for the specific mutation. Results typically take a few weeks. Your doctor will discuss which embryos are unaffected (or carriers, if that is relevant) and suitable for transfer. The transfer is a simple procedure, and any remaining unaffected embryos can be frozen for future use.

Questions to Ask Your Clinic

• What is your experience with PGT-M for my specific condition?
• Which genetic laboratory do you work with, and is it accredited?
• How long does it take to get PGT-M results?
• What are the costs involved, and what is included?
• What are the limitations of PGT-M for my case?

Next Steps: Your Checklist

1. Gather your genetic test reports and medical history.
2. Schedule a genetic counseling session.
3. Research IVF clinics in Thailand that offer PGT-M.
4. Contact clinics to ask about their process and requirements.
5. Confirm the timeline and costs before starting treatment.

For more information on PGT in Thailand, visit our PGT in Thailand page. You can also explore our guides and FAQ for additional insights.

Frequently asked questions

What is the difference between PGT-M and PGT-A?

PGT-M tests for a specific genetic disorder, while PGT-A screens for chromosomal abnormalities (aneuploidy). They are different tests with different purposes.

Do I need a referral to get PGT-M in Thailand?

You do not need a formal referral, but you will need a confirmed genetic diagnosis and a consultation with the IVF clinic. The clinic may require you to work with a genetic counselor.

How long does the PGT-M process take?

The entire process, from initial consultation to embryo transfer, can take several months. The genetic testing itself may take a few weeks, but the timeline varies by clinic and laboratory.

Is PGT-M guaranteed to prevent a genetic disorder?

No, PGT-M is highly accurate but not 100% guaranteed. There is a small risk of misdiagnosis, and it does not test for all genetic conditions. Discuss the limitations with your doctor.

Continue your research

• PGT in Thailand overview
• PGT and IVF guides
• Frequently asked questions

Medical information notice: This article is educational and does not replace individual assessment, diagnosis, genetic counselling or treatment advice from a licensed clinician. Provider services, availability, fees and policies should be verified directly before booking.