How to Verify a Fertility Clinic’s Genetics Laboratory: A Patient Checklist

Why verifying the genetics laboratory matters

When you are considering IVF with preimplantation genetic testing (PGT), the genetics laboratory plays a central role in the accuracy and reliability of your results. The quality of the lab, the experience of the team, and the clarity of their processes can affect your decision-making at every step. This guide helps you ask the right questions and gather the information you need to compare clinics with confidence.

At a glance: what to check

• Accreditation and certifications of the genetics lab
• Types of genetic tests offered and their limitations
• Biopsy procedure: who performs it and when
• Transport logistics if samples are sent to an external lab
• Counseling and support before and after testing
• Turnaround time for results and how you will receive them

Accreditation and quality standards

Start by asking about the laboratory’s accreditations and quality management systems. Look for recognized international standards, such as ISO 15189, which specifies requirements for quality and competence in medical laboratories. Also ask if the lab participates in external quality assessment (EQA) programs, which test their proficiency against other labs. These details give you a baseline for reliability.

Questions to ask:

• What accreditations does the genetics laboratory hold?
• How often is the lab inspected, and by which body?
• Does the lab participate in external quality assessment schemes?
• Can you provide documentation of recent quality audits?

Types of genetic tests and their scope

PGT can screen for chromosomal abnormalities (PGT-A), specific genetic disorders (PGT-M), or structural rearrangements (PGT-SR). Each test has different capabilities and limitations. Ask the clinic which tests they offer and whether they are performed in-house or referred to an external laboratory. Also ask about the technology used, such as next-generation sequencing (NGS) or array comparative genomic hybridization (aCGH), and what the test can and cannot detect.

Questions to ask:

• Which PGT tests do you offer (PGT-A, PGT-M, PGT-SR)?
• Are these tests performed in your own lab or sent to an external facility?
• What technology is used, and what are its limitations?
• How do you handle cases where the test result is inconclusive?

Biopsy procedure and embryo handling

The biopsy is a delicate step where a few cells are removed from the embryo for testing. Ask about the experience of the embryology team, the stage at which the biopsy is performed (usually on day 5 or 6), and how the embryos are handled and labeled to avoid mix-ups. Also ask about the criteria for embryo freezing and the survival rates after thawing, if relevant.

Questions to ask:

• Who performs the biopsy, and what is their experience?
• At what stage are embryos biopsied?
• How do you ensure accurate labeling and traceability of embryos?
• What is your policy on embryos that do not survive the biopsy or freezing process?

Transport logistics for external labs

If the clinic sends samples to an external genetics laboratory, you need to understand the logistics. Ask about the courier service, the temperature control during transport, and the chain of custody. Also ask how long the transport takes and whether there is any risk of sample degradation. This is especially important for international patients who may be coordinating from abroad.

Questions to ask:

• If samples are sent to an external lab, how are they transported?
• What measures are in place to maintain sample integrity during transport?
• How long does transport take, and how does that affect the timeline?
• Who is responsible if a sample is lost or damaged in transit?

Turnaround time and result reporting

Knowing how long it takes to get results is crucial for planning your treatment cycle. Ask for the typical turnaround time for each type of test, and whether it includes the time for transport if applicable. Also ask how results are communicated to you—whether through a genetic counselor, a doctor, or a written report—and whether you will have a chance to discuss the implications before making decisions.

Questions to ask:

• What is the typical turnaround time for PGT results?
• How will I receive my results, and who will explain them to me?
• Will I have a follow-up consultation to discuss the results?
• What happens if the results are unclear or need further testing?

Counseling and support

Genetic testing can bring complex emotional and medical information. Ask about the availability of genetic counseling before and after testing. A good clinic will offer support to help you understand the implications of the results, including the risks of passing on genetic conditions and the options available to you. This is not just a medical decision but a personal one.

Questions to ask:

• Is genetic counseling available before and after testing?
• Who provides the counseling—a genetic counselor, a doctor, or both?
• How do you support patients who receive unexpected or difficult results?
• Are there any additional costs for counseling services?

Comparing clinics: a practical approach

When comparing clinics, create a simple table to record your findings. Use the same set of questions for each clinic so you can compare apples to apples. Consider factors like accreditation, test types, biopsy experience, transport logistics, turnaround time, and counseling support. Also think about the overall communication and transparency you experience during your inquiries—this can be a good indicator of how the clinic operates.

Here is a sample comparison table you can use:

Criteria	Clinic A	Clinic B	Clinic C
Accreditation
Tests offered
Biopsy experience
Transport logistics
Turnaround time
Counseling support

Next steps: your checklist

Before you commit to a clinic, take these steps:

1. List your questions and send them to the clinic in writing.
2. Ask for documentation of accreditations and quality standards.
3. Clarify whether the lab is in-house or external, and understand the logistics.
4. Ask about the specific tests you may need and their limitations.
5. Inquire about counseling services and how results will be explained.
6. Compare your findings across clinics using a consistent checklist.
7. Trust your instincts about the clinic’s transparency and communication.

Remember, verifying the genetics laboratory is about ensuring you have the information you need to make informed decisions. Take your time, ask questions, and choose a clinic that aligns with your needs and values.

Frequently asked questions

What is the most important thing to verify about a genetics laboratory?

Accreditation and participation in external quality assessment are key indicators of a lab's reliability. Ask for documentation and details about their quality management systems.

Should I choose a clinic with an in-house genetics lab or one that sends samples externally?

Both can be reliable. In-house labs may offer faster turnaround and more direct communication, while external labs may have specialized expertise. Ask about transport logistics and how results are reported.

How long does it typically take to get PGT results?

Turnaround times vary depending on the test type and whether the lab is in-house or external. Ask the clinic for their specific timeline, including any transport time.

What should I do if I receive unexpected genetic results?

A good clinic will provide genetic counseling to help you understand the implications and explore your options. Ask about counseling services before you start treatment.

Continue your research

• Thailand hospital directory
• Patient resources
• Prepare a private case review

Medical information notice: This article is educational and does not replace individual assessment, diagnosis, genetic counselling or treatment advice from a licensed clinician. Provider services, availability, fees and policies should be verified directly before booking.