At a glance
For women under 35, PGT-A can improve embryo selection, but success depends on many factors beyond age. Learn how PGT-A works, its benefits, and what to ask clinics in Thailand.
What Is PGT-A and How Does It Relate to Age?
Preimplantation Genetic Testing for Aneuploidy (PGT-A) screens embryos for chromosomal abnormalities before transfer. For women under 35, the chance of producing chromosomally normal embryos is generally higher than for older women. However, PGT-A does not guarantee a pregnancy or live birth—it helps select embryos with the correct number of chromosomes, which may reduce the risk of miscarriage and failed implantation.
Does PGT-A Improve Success for Younger Women?
Research suggests that for women under 35, PGT-A can increase the per-transfer implantation rate by avoiding aneuploid embryos. However, the overall live birth rate per cycle may not differ significantly because many younger women already have a high proportion of normal embryos. The main benefit is often a shorter time to pregnancy by transferring a euploid embryo first, rather than attempting multiple transfers with untested embryos.
Clinic Variability in Thailand
Success rates for PGT-A vary among clinics in Thailand due to differences in laboratory protocols, embryologist expertise, and biopsy techniques. Some clinics may report higher implantation rates after PGT-A, but these figures are not standardized. When comparing clinics, ask for their specific PGT-A outcomes for women under 35, including the number of cycles, euploidy rates, and live birth rates per transfer.
Benefits and Limitations of PGT-A
Potential Benefits
- Reduced risk of miscarriage from chromosomal abnormalities
- Higher implantation rate per transfer
- Fewer failed transfers and shorter time to pregnancy
- Possibility of single embryo transfer, lowering multiple pregnancy risk
Limitations
- PGT-A cannot detect all genetic disorders or structural abnormalities
- Embryo biopsy carries a small risk of damage (though low with experienced labs)
- Mosaic embryos (with both normal and abnormal cells) may be discarded unnecessarily
- PGT-A does not guarantee a healthy baby
- Cost and time added to the IVF cycle
Questions to Ask Your Clinic
- What is your euploidy rate for women under 35?
- What is your live birth rate per transfer after PGT-A for this age group?
- How do you handle mosaic embryos?
- What is your biopsy technique and experience?
- What are the additional costs for PGT-A?
Alternatives to PGT-A
For women under 35 with no known genetic issues, some clinics may recommend transferring untested embryos, especially if the patient has a good prognosis. Other options include time-lapse imaging or preimplantation genetic screening for specific conditions (PGT-M or PGT-SR) if indicated. Discuss with your doctor whether PGT-A is likely to add value in your case.
Next Steps
If you are considering PGT-A in Thailand, start by consulting with a fertility specialist to review your medical history and goals. Request detailed success data from clinics and ask about their experience with younger patients. Remember that PGT-A is a tool to aid selection, not a guarantee of outcome.
Frequently asked questions
Is PGT-A recommended for all women under 35?
No. PGT-A is typically recommended for women with recurrent miscarriage, previous aneuploidy, or advanced maternal age. For younger women with no known issues, the benefit may be smaller. Discuss with your doctor whether PGT-A is appropriate for you.
What is the euploidy rate for women under 35?
Euploidy rates vary by clinic and individual factors, but generally, women under 35 have a higher proportion of normal embryos compared to older women. Exact figures should be obtained from your clinic.
Does PGT-A increase the chance of a live birth?
PGT-A can improve the per-transfer live birth rate by selecting euploid embryos, but the overall live birth rate per cycle may not differ significantly for younger women. It may reduce time to pregnancy by avoiding failed transfers.
What are the risks of PGT-A?
Risks include embryo damage from biopsy (rare with experienced labs), the possibility of discarding mosaic embryos that could implant, and the added cost and time. PGT-A does not guarantee a healthy baby.
How much does PGT-A cost in Thailand?
Costs vary by clinic and the number of embryos tested. Contact clinics directly for a detailed fee schedule. PGT-A is an additional expense on top of standard IVF costs.
Continue your research
Medical information notice: This article is educational and does not replace individual assessment, diagnosis, genetic counselling or treatment advice from a licensed clinician. Provider services, availability, fees and policies should be verified directly before booking.
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