At a glance

Low AMH does not automatically disqualify you from IVF with PGT in Thailand, but it affects egg yield, embryo numbers, and testing feasibility. Learn what to consider and what questions to ask your clinic.

Can you do IVF with PGT in Thailand if you have low AMH?

Yes, having a low Anti-Müllerian Hormone (AMH) level does not automatically prevent you from undergoing IVF with preimplantation genetic testing (PGT) in Thailand. However, it does influence how your cycle is planned, the number of eggs you are likely to produce, and whether PGT will be feasible. This article explains the key differences, uncertainties, and questions you should discuss with your treating clinic.

How low AMH affects IVF cycle planning

AMH is a hormone produced by small ovarian follicles and is used as a marker of ovarian reserve. A low AMH indicates a reduced number of remaining eggs. In an IVF cycle, this typically means you may produce fewer eggs in response to stimulation medications compared to someone with normal AMH. Clinics in Thailand may adjust your stimulation protocol—for example, using higher doses of gonadotropins or adding growth hormone—to try to maximize follicle recruitment. However, individual response varies, and there is no guarantee that any specific protocol will increase egg yield.

Expected number of eggs with low AMH

While exact numbers cannot be predicted, women with low AMH often retrieve fewer than 10 eggs per cycle, and sometimes as few as 1–4. The number of eggs retrieved directly affects how many embryos can be created and, consequently, how many can be biopsied for PGT. PGT requires a biopsy of a few cells from each embryo, and not all embryos will survive the biopsy or be genetically normal. Therefore, a lower starting egg count reduces the likelihood of having at least one genetically normal embryo available for transfer.

PGT feasibility with low AMH

PGT can still be performed even if only a few embryos are obtained. However, the chance of having a transferable embryo after PGT depends on the number of embryos that reach the blastocyst stage (day 5–6) and their genetic status. For some patients, especially those with advanced maternal age or known genetic conditions, the attrition rate can be high. It is important to have realistic expectations: with very few eggs, the probability of ending a cycle with no embryos suitable for transfer is higher.

Important distinctions and uncertainties

  • AMH is not the only factor: Age, antral follicle count (AFC), and previous response to stimulation also matter. A low AMH in a younger woman may still yield a reasonable number of eggs.
  • PGT-A vs. PGT-M: PGT for aneuploidy (PGT-A) screens for chromosomal abnormalities, while PGT for monogenic disorders (PGT-M) tests for specific genetic conditions. The type of PGT may affect the number of embryos needed and the cost.
  • Cycle cancellation risk: Some cycles may be cancelled before egg retrieval if the ovaries do not respond adequately. Discuss cancellation criteria with your clinic.
  • No guaranteed outcomes: No clinic can guarantee a specific number of eggs, embryos, or a live birth. Success rates vary widely and depend on individual factors.

Questions to ask your clinic

  • What stimulation protocol do you recommend for low AMH, and why?
  • What is your clinic’s experience with patients who have similar AMH levels and age?
  • How many eggs do you typically retrieve from patients with my AMH level?
  • What is the expected blastocyst formation rate from those eggs?
  • What is the cost of PGT, and are there any package options if the cycle does not proceed to biopsy?
  • What is your policy on cycle cancellation, and what are the associated costs?
  • Do you recommend any additional tests (e.g., genetic carrier screening, sperm DNA fragmentation) before starting?

Related reading

Frequently asked questions

What is a low AMH level?

AMH levels are measured in ng/mL or pmol/L, and what is considered 'low' depends on age and laboratory reference ranges. Generally, levels below 1.0 ng/mL (or 7.1 pmol/L) are often considered low, but your doctor will interpret your result in context.

Can I improve my AMH level?

AMH reflects the current pool of eggs and does not significantly increase with supplements or lifestyle changes. Some studies suggest that vitamin D or DHEA may help in certain cases, but evidence is limited. Focus on optimizing egg quality rather than quantity.

How many IVF cycles might I need with low AMH?

There is no set number. Some patients may need multiple cycles to accumulate enough embryos for PGT. Discuss a treatment plan that considers the possibility of multiple cycles and associated costs.

Is PGT worth it if I only get a few embryos?

PGT can still provide valuable information, especially if you have a known genetic condition or are at high risk for aneuploidy. However, with very few embryos, the chance of having a normal embryo to transfer is lower. Weigh the cost and potential benefit with your doctor.

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Medical information notice: This article is educational and does not replace individual assessment, diagnosis, genetic counselling or treatment advice from a licensed clinician. Provider services, availability, fees and policies should be verified directly before booking.

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