At a glance
A plain-English guide to PGT-A for international patients: what it screens for, how it is performed, what results can and cannot tell you, and what to confirm with your clinic in Thailand.
PGT-A (preimplantation genetic testing for aneuploidy) is a laboratory test performed on a small number of cells taken from an embryo during IVF. It looks for extra or missing chromosomes, a condition called aneuploidy. PGT-A does not diagnose a disease in the future child, does not guarantee a pregnancy, and does not replace other fertility assessments. It is one tool among many that you and your clinician may consider. In Thailand, as elsewhere, availability, laboratory arrangements, costs and legal requirements can vary, so confirm details directly with the clinic you are considering.
At a glance
- PGT-A examines chromosome number in an embryo, not specific gene mutations.
- It is usually done as part of an IVF cycle, with a biopsy at a defined embryo stage.
- Results are reported as euploid, aneuploid, mosaic or sometimes inconclusive.
- PGT-A cannot guarantee implantation, live birth or a healthy child.
- Ask each clinic how it performs the test, who analyses the sample, and what happens to embryos with different results.
What is PGT-A and what does it screen for?
PGT-A is a chromosome screening test. It counts chromosomes or looks for large missing or extra chromosome segments in the cells sampled from an embryo. The typical human embryo has 46 chromosomes in 23 pairs. A result showing a different number is called aneuploidy. Common examples include trisomy (an extra chromosome) and monosomy (a missing chromosome).
PGT-A is different from PGT-M, which looks for a specific inherited condition, and from PGT-SR, which looks at structural chromosome rearrangements. If you are researching PGT-A questions in Thailand, make sure the clinic is clear about which test is being discussed, because the purpose and the laboratory method differ.
How is PGT-A performed during an IVF cycle?
The exact protocol is clinic-specific, but the general sequence is similar in most settings:
- Ovarian stimulation and egg retrieval — eggs are collected after a stimulation cycle.
- Fertilisation — eggs are fertilised in the laboratory, either by conventional insemination or by intracytoplasmic sperm injection (ICSI), depending on the clinical situation.
- Embryo culture — embryos are grown for several days. Biopsy is often performed at the blastocyst stage, commonly around day 5 or day 6, but timing can vary.
- Biopsy — a few cells are removed from the trophectoderm, the outer layer that later forms the placenta. The embryo itself is not usually destroyed by this procedure.
- Sample analysis — the biopsied cells are sent to a genetics laboratory. Some clinics analyse in-house; others send samples to a partner laboratory, sometimes abroad.
- Embryo freezing and storage — because analysis takes time, embryos are typically vitrified (frozen) while waiting for results.
- Results and transfer planning — once results are available, you and your clinician discuss which embryo(s), if any, to transfer in a later cycle.
Ask your clinic who performs the biopsy, which laboratory analyses the sample, how long results usually take, and how embryos are stored in the meantime. These are practical questions that affect planning and cost.
What do PGT-A results mean?
Results are usually placed into a few broad categories. Wording varies between laboratories, so ask for the exact terms your clinic uses.
| Result category | General meaning | What it does not tell you |
|---|---|---|
| Euploid | The sample showed the expected number of chromosomes. | It does not guarantee implantation, ongoing pregnancy or a healthy baby. |
| Aneuploid | The sample showed an extra or missing chromosome. | It does not predict the exact health outcome of that embryo, and clinics differ in whether such embryos are transferred, discarded or used for research. |
| Mosaic | The sample contained a mix of cells with different chromosome numbers. | The clinical significance can be uncertain, and counselling is important before deciding what to do. |
| Inconclusive or no result | The laboratory could not produce a clear result. | It does not mean the embryo is abnormal; it means the test did not give a usable answer. |
PGT-A is a screening test, not a diagnostic test for every possible genetic issue. It does not detect all chromosomal abnormalities, single-gene disorders, or structural problems. A euploid result reduces, but does not eliminate, the chance of miscarriage or chromosome-related conditions. For these reasons, PGT-A is best understood as one part of a broader clinical picture.
Who might consider PGT-A?
PGT-A is not routinely recommended for every IVF patient. Guidelines and professional opinions differ, and the decision is individual. Some situations where it may be discussed include:
- A history of recurrent pregnancy loss.
- Previous IVF cycles with unsuccessful implantation.
- Advanced maternal age, where the proportion of aneuploid embryos tends to be higher.
- A preference to prioritise embryos for transfer based on chromosome screening, after counselling about the limitations.
This is not a complete list, and it is not a set of eligibility criteria. Whether PGT-A is appropriate for you depends on your medical history, your goals, and the advice of your treating clinician. No website, including this one, can determine that for you.
PGT-A for international patients: practical planning questions
If you are travelling to Thailand for IVF and considering PGT-A, the logistics matter as much as the science. Because rules, prices and paperwork can change, treat the following as categories to confirm rather than fixed facts.
- Clinic and laboratory arrangements — Does the clinic perform PGT-A on site, or send samples to another laboratory? Who communicates results to you?
- Cost components — Ask for a written breakdown: biopsy, genetic analysis, embryo freezing, storage, and any courier or administrative fees. Prices vary and are not standardised.
- Timeline — How many days after biopsy are results typically available? Does this affect your travel dates or require a second trip?
- Consent and counselling — What counselling is offered before testing and before decisions about mosaic or aneuploid embryos?
- Documents and legal requirements — What identification, consent forms or other documents does the clinic require from international patients? Confirm current requirements with the clinic and, where relevant, official authorities.
- Language and follow-up — Is interpretation available? Who do you contact with questions after you return home?
Questions to ask a clinic about PGT-A
Bring a written list. Clear answers help you compare clinics and understand what you are agreeing to.
- Which specific PGT test do you recommend for my situation, and why?
- At what embryo stage is the biopsy taken, and who performs it?
- Which laboratory analyses the sample, and what is its experience with PGT-A?
- How are results reported, and what do you do with mosaic or inconclusive results?
- What are the known limitations of PGT-A in your practice?
- What are all the costs involved, including storage and any repeat testing?
- What happens if no embryo is suitable for transfer after testing?
- What support is available if we need to make difficult decisions about embryo disposition?
Next steps for your research
PGT-A is a laboratory tool that can provide useful information in some situations, but it is not a guarantee of any outcome. A careful decision usually involves reviewing your medical history with a qualified clinician, asking how the test would change your treatment plan, and understanding the emotional and financial implications.
To continue learning, you can read our overview of PGT in Thailand, browse the frequently asked questions, explore other patient guides, or contact us with general questions. For medical advice, always speak with your treating clinic.
Frequently asked questions
Does PGT-A guarantee a healthy baby?
No. PGT-A screens for extra or missing chromosomes in the sampled cells, but it cannot guarantee implantation, a live birth, or a child without health conditions. It does not detect every genetic or structural issue, and pregnancy outcomes depend on many factors beyond chromosome number.
Is PGT-A the same as PGT-M or PGT-SR?
No. PGT-A looks at chromosome number across the embryo's chromosomes. PGT-M looks for a specific inherited condition, and PGT-SR looks at structural chromosome rearrangements. The laboratory methods and the reasons for testing differ, so ask your clinic which test is being recommended and why.
What happens if my embryo is reported as mosaic?
A mosaic result means the sample contained a mix of cells with different chromosome numbers. The clinical significance can be uncertain, and practices vary. Ask your clinic for counselling about what a mosaic result may mean for your specific embryo and what options are available.
Can I have PGT-A done in Thailand as an international patient?
Many international patients travel to Thailand for IVF, and some clinics offer PGT-A. Availability, laboratory arrangements, costs, timelines and documentation requirements vary. Confirm current details directly with the clinic you are considering and, where relevant, with official authorities.
How long does it take to get PGT-A results?
Turnaround time depends on the clinic and the laboratory analysing the sample. Some results may be available within a few days, while others take longer, especially if samples are sent to another laboratory. Ask your clinic for a realistic estimate and how it affects your travel plans.
Continue your research
Medical information notice: This article is educational and does not replace individual assessment, diagnosis, genetic counselling or treatment advice from a licensed clinician. Provider services, availability, fees and policies should be verified directly before booking.
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