PGT-M Cost in Thailand: A Checklist for Comparing Quotes

If you are considering preimplantation genetic testing for monogenic disorders (PGT-M) in Thailand, understanding the cost structure is essential for planning. PGT-M involves several steps, each with its own fee, and the total can vary significantly between clinics. This guide explains the typical cost components and provides a checklist of questions to ask when comparing quotes.

At a Glance: PGT-M Cost Components

• Probe development (creating a genetic test specific to your family’s mutation)
• IVF cycle fees (stimulation, egg retrieval, embryo culture)
• Embryo biopsy (removing a few cells from each embryo)
• Genetic testing per embryo (the actual PGT-M analysis)
• Additional lab fees (e.g., shipping, storage, or re-testing)

Understanding the Cost Breakdown

PGT-M is a personalized process. Unlike standard IVF, it requires a custom genetic test for each family’s specific mutation. This is why the cost is often higher than other types of PGT. Here are the main components you will see in a quote:

Probe Development

Before any embryos can be tested, a laboratory must create a ‘probe’ or test that can identify the specific genetic variant in your family. This usually requires blood samples from you, your partner, and sometimes other family members. The cost for this step is typically a one-time fee, but it is essential for the entire process.

IVF Cycle Fees

PGT-M requires IVF to create embryos. The IVF cycle includes medications for ovarian stimulation, ultrasound and blood test monitoring, the egg retrieval procedure, and laboratory work to fertilize the eggs and culture the embryos. These fees are usually separate from the genetic testing costs.

Embryo Biopsy

On day 5 or 6 of embryo development, a specialist removes a few cells from each embryo (trophectoderm biopsy). This is a delicate procedure that requires specialized equipment and expertise. The biopsy fee is often charged per embryo or as a flat rate per cycle.

Genetic Testing per Embryo

The biopsied cells are sent to a genetics laboratory for analysis. The lab tests each embryo for the specific mutation (PGT-M) and may also check for chromosomal abnormalities (PGT-A) if you choose. This fee is typically per embryo, so the total depends on how many embryos you have.

Additional Lab Fees

Some clinics charge extra for shipping samples to an external lab, storing embryos, or repeating tests if results are inconclusive. Ask about these potential extras upfront.

Why Prices Vary Between Clinics

Several factors influence the total cost of PGT-M in Thailand:

• Clinic location: Clinics in Bangkok may have higher overheads than those in other cities.
• Laboratory accreditation: Labs with international accreditation may charge more for their services.
• In-house vs. external lab: If the clinic has its own genetics lab, the cost may be bundled; otherwise, you may pay separate fees.
• Number of embryos tested: Since testing is per embryo, the more embryos you have, the higher the total cost.
• Additional testing: Adding PGT-A (chromosomal screening) or other tests will increase the price.

Questions to Ask When Comparing Quotes

To get a clear picture of the total cost, ask each clinic the following questions:

• What is the fee for probe development, and what does it include?
• Are the IVF cycle fees and genetic testing fees separate?
• Is the embryo biopsy fee included in the IVF cycle or charged separately?
• What is the cost per embryo for PGT-M testing?
• Are there any additional lab fees, such as shipping, storage, or re-testing?
• Do you offer a package price that includes all steps?
• What is your policy if no embryos are suitable for transfer?
• Are there any discounts for multiple cycles?

Next Steps: Your Cost-Comparison Checklist

1. List the clinics you are considering.
2. Request a detailed written quote from each, itemizing all components.
3. Ask the questions above and note the answers.
4. Compare the total estimated cost, not just the headline price.
5. Consider the clinic’s experience with PGT-M and the laboratory’s accreditation.
6. Factor in travel and accommodation if you are coming from abroad.
7. Confirm what happens if you need more than one cycle.

For more information on the PGT process, see our PGT in Thailand guide. To understand IVF costs, visit IVF cost in Thailand. For additional support, explore our patient resources or contact us.

Frequently asked questions

What is included in a PGT-M quote?

A PGT-M quote typically includes probe development, IVF cycle fees, embryo biopsy, and genetic testing per embryo. However, some clinics may bundle these, while others itemize them. Always ask for a detailed breakdown.

Why is PGT-M more expensive than PGT-A?

PGT-M requires a custom genetic test (probe) for each family's specific mutation, which involves additional laboratory work and often requires samples from family members. PGT-A, which screens for chromosomal abnormalities, uses a standardized test and is generally less costly.

Are there any hidden costs in PGT-M treatment?

Potential additional costs include shipping of samples to an external lab, embryo storage, re-testing if results are inconclusive, and medications. Ask your clinic for a complete list of possible fees.

Can I get a refund if no embryos are suitable for transfer?

Refund policies vary by clinic. Some may offer partial refunds for unused testing or cycle fees, while others may not. It is important to clarify this before starting treatment.

Continue your research

• PGT in Thailand overview
• IVF cost planning
• Patient resources

Medical information notice: This article is educational and does not replace individual assessment, diagnosis, genetic counselling or treatment advice from a licensed clinician. Provider services, availability, fees and policies should be verified directly before booking.