At a glance
Understand what each type of preimplantation genetic testing is designed to investigate—and what it cannot promise.
PGT is not one test and it is not automatically part of every IVF cycle. The right conversation begins with a specific clinical question, informed consent and a clear understanding of possible results.
The three terms in plain English
PGT-A provides information about chromosome number in sampled embryo cells. PGT-M is designed around a known single-gene condition. PGT-SR may be used when a parent carries a structural chromosome rearrangement.
- PGT-A: chromosome-number screening
- PGT-M: a known monogenic condition
- PGT-SR: a documented structural rearrangement
Why testing is not a guarantee
An embryo result cannot guarantee implantation, pregnancy, live birth or the health of a future child. Sampling, laboratory limits, mosaic findings and the many non-genetic factors involved in pregnancy all matter.
Patients should ask how the clinic reports mosaic or no-result findings, whether genetic counselling is available and what confirmatory prenatal testing may later be discussed.
Questions for your consultation
A useful consultation should connect the proposed test to your history—not simply add it to a package.
- What clinical question are we trying to answer?
- What are the alternatives, including not testing?
- What results might the laboratory report?
- How will abnormal, mosaic or no-result findings be managed?
- Will a genetic counsellor review our case?
Evidence trail
Sources & verification
Review current primary information and reconfirm provider services, fees and eligibility before booking.
01ASRM PGT-A committee opinion (2024) ↗02ASRM PGT-M committee opinion (2023) ↗Need help turning research into a shortlist?
