PGT is not one test and it is not automatically part of every IVF cycle. The right conversation begins with a specific clinical question, informed consent and a clear understanding of possible results.
The three terms in plain English
PGT-A provides information about chromosome number in sampled embryo cells. PGT-M is designed around a known single-gene condition. PGT-SR may be used when a parent carries a structural chromosome rearrangement.
- PGT-A: chromosome-number screening
- PGT-M: a known monogenic condition
- PGT-SR: a documented structural rearrangement
Why testing is not a guarantee
An embryo result cannot guarantee implantation, pregnancy, live birth or the health of a future child. Sampling, laboratory limits, mosaic findings and the many non-genetic factors involved in pregnancy all matter.
Patients should ask how the clinic reports mosaic or no-result findings, whether genetic counselling is available and what confirmatory prenatal testing may later be discussed.
Questions for your consultation
A useful consultation should connect the proposed test to your history—not simply add it to a package.
- What clinical question are we trying to answer?
- What are the alternatives, including not testing?
- What results might the laboratory report?
- How will abnormal, mosaic or no-result findings be managed?
- Will a genetic counsellor review our case?
Sources & verification
Sources are provided so readers can review current primary information. Provider services and credentials should be reconfirmed before booking.
ASRM PGT-A committee opinion (2024) →ASRM PGT-M committee opinion (2023) →Need help turning research into a shortlist?